Our Process R&D team has extensive expertise in developing and scaling up multi-step processes for complex molecules, including heterocycles, carbohydrates, nucleosides and nucleotides, organometallic compounds, vitamin D analogues, peptides, and prostaglandins. We have successfully developed and commercialized several advanced transformations such as asymmetric syntheses, Suzuki, Sonogashira, Kumada and Heck couplings, turbo Grignard reactions, classical halogenations, carbonylation, ozonolysis, Buchwald amination, and chiral reductions, among others.
We have also established standardized internal procedures for the safe and efficient handling of sensitive reagents and catalysts, ensuring reliability and reproducibility at scale. Our scientists are highly skilled in all aspects of process development, including route scouting, alternate reagent and catalyst screening, solvent selection, impurity profiling, and implementation of robust impurity control strategies.

Why Choose VIVA?
• Extensive expertise across diverse chemistries, including the safe and efficient handling of sensitive reagents, catalysts, and complex compound classes.
• Integrated technology platforms that complement and accelerate process development activities.
• State-of-the-art infrastructure, tools, and methodologies enabling efficient, reliable, and scalable process development.
• Close collaboration with process engineering teams to ensure smooth scale-up and successful technology transfer.

Early Phase Process Scale-Up:

Phase-Appropriate Development & Manufacturing for Pre-Clinical and Phase I NCEs
We provide agile and efficient support to innovator companies through phase-appropriate development and manufacturing services tailored for pre-clinical and Phase I new chemical entities (NCEs), ensuring speed, quality, and compliance.

Infrastructure Highlights

• Laboratory Reactors: 2 L to 10 L scale for early-stage development.
• Kilo Lab Suites: 64 L to 250 L reactors at our Research & Technology facility.
• Process Engineering Block: Designed to mimic larger-scale equipment for seamless scale-up.
• Flexible Reactor Capacity: 64 L up to 3 KL reactors available for diverse process needs.